| CAS NO: | 24198-95-6 |
| 包装 | 价格(元) |
| 1mg (solution) | 电议 |
| 5mg (solution) | 电议 |
| 10mg (solution) | 电议 |
| Physical Appearance | A solution in ethanol. To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. |
| Storage | Store at -20°C |
| M.Wt | 266.38 |
| Cas No. | 24198-95-6 |
| Formula | C16H26O3 |
| Solubility | ≤12mg/ml in ethanol;10mg/ml in DMSO;14mg/ml in dimethyl formamide |
| Chemical Name | (2E,6E)-methyl 9-(3,3-dimethyloxiran-2-yl)-3,7-dimethylnona-2,6-dienoate |
| Canonical SMILES | COC(/C=C(C)/CC/C=C(CCC1OC1(C)C)\C)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Juvenile hormone III is an acyclic sesquiterpenoid that regulates diverse processes in insects, including adult transition of larvae and oogenesis in adult females[1,2]. It activates the juvenile hormone receptor, known as methoprene-tolerant, with a Kd value of 2.9 nM.2 Juvenile hormone III can be synthesized from farnesoic acid by two alternative pathways, one through methyl farnesoate and the other through juvenile hormone acid III[3,4].
References：
[1]. Tillman J A, Seybold S J, Jurenka R A, et al. Insect pheromones--an overview of biosynthesis and endocrine regulation. Insect Biochemistry and Molecular Biology, 1999, 29(6): 481-514.
[2]. Charles J P, Iwema T, Epa V C, et al. Ligand-binding properties of a juvenile hormone receptor, methoprene-tolerant. Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(52): 21128-21133.
[3]. Defelipe L A, Dolghih E, Roitberg A E, et al. Juvenile hormone synthesis: "Esterify then epoxidize" or "epoxidize then esterify"? Insights from the structural characterization of juvenile hormone acid methyltransferase. Insect Biochemistry and Molecular Biology, 2011, 41(4): 228-235.
[4]. Navare A T, Mayoral J G, Nouzova M, et al. Rapid direct analysis in real time (DART) mass spectrometric detection of juvenile hormone III and its terpene precursors. Analytical and Bioanalytical Chemistry, 2010, 398(7-8): 3005-3013.
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