化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 218.33 |
Cas No. | 471-05-6 |
Formula | C15H22O |
Solubility | insoluble in H2O; ≥44.4 mg/mL in EtOH; ≥81.4 mg/mL in DMSO |
Chemical Name | (2Z,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trienone |
Canonical SMILES | C/C1=C/CC/C(C)=C/CC(C)(C)/C=C/C1=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger),which exhibits antitumor activity[1].Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts.
参考文献:
[1]Kamalidehghan B, Ahmadipour F, Noordin M I. DNA Fragmentation Is Not Associated with Apoptosis in Zerumbone-induced HepG2 Cells[J]. Iranian Biomedical Journal, 2012, 16(4):226.