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HIV-1 integrase inhibitor 3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
HIV-1 integrase inhibitor 3图片
CAS NO:1638504-56-9
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
HIV-1 integrase inhibitor 3 是一种 HIV-1 整合酶链转移 (INST) 抑制剂，其 IC50 值为 2.7 nM。
Cas No.1638504-56-9
Canonical SMILESNC(C1=CC(CCCCCO)=CN=C1N2O)=C(C(NCC3=CC=C(F)C=C3F)=O)C2=O
分子式C21H22F2N4O4
分子量432.42
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. IC50: 2.7 nM (INST)[1]

HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].

[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.