您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Glabranine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Glabranine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glabranine图片
CAS NO:41983-91-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Glabranine 是从 Tephrosia s.p 中分离出一种类黄酮,在体外对登革病毒发挥抑制作用。Glabranine 与 DENV 2 型 (DENV2) E 蛋白的可溶性胞外域形成相互作用。
Cas No.41983-91-9
别名光甘草宁;欧亚甘草宁;裸禾蕨黄素
Canonical SMILESO=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2O[C@H](C3=CC=CC=C3)C1
分子式C20H20O4
分子量324.37
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus[1].Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein[2].

[1]. SÁnchez I, et al. Antiviral effect of flavonoids on the dengue virus. Phytother Res. 2000 Mar;14(2):89-92. [2]. Ismail NA, et al. Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. Interdiscip Sci. 2017 Dec;9(4):499-511.