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ZK-90055 hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
ZK-90055 hydrochloride图片
CAS NO:84638-81-3
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
ZK-90055hydrochloride是β2肾上腺素能受体(β2adrenergicreceptor)激动剂。
Cas No.84638-81-3
Canonical SMILESO=C(C(N1)=CC2=C1C(O)=CC=C2C(O)CNC(C)(C)C)OC.[H]Cl
分子式C16H23ClN2O4
分子量342.82
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ZK-90055 hydrochloride is a β2 adrenergic receptor agonist.

Contrasting a pro-drug, a soft-drug is active per se when given locally but is rapidly inactivated when it reaches the general circulation. Thus, a long duration of action at a minimum of systemic side effects may be achieved after inhalation of a h2-agonist designed in this way. One such example is ZK-90055, an indol derivative with a hydrolysable ester bond on the ring system. The development of ZK-90055 is stopped before clinical trials are commenced[2].

[1]. Waldeck B, et al. beta-Adrenoceptor agonists after terbutaline. Pharmacol Toxicol. 1995;77 Suppl 3:25-9. [2]. Waldeck B, et al. Beta-adrenoceptor agonists and asthma--100 years of development. Eur J Pharmacol. 2002 Jun 7;445(1-2):1-12.