| CAS NO: | 127171-88-4 |
| 包装: | 1mg |
| 市场价: | 4680元 |
Chitohexaosehexahydrochloride是具有抗炎作用的壳聚糖低聚糖。Chitohexaosehexahydrochloride与TLR4的活性位点结合并抑制LPS诱导的炎症。
| Cas No. | 127171-88-4 |
| 别名 | 壳六糖六盐酸盐 |
| Canonical SMILES | OC[C@@H](O[C@H]1O[C@@H]([C@@H]([C@H]2N)O)[C@H](O[C@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@@H](N)C=O)CO)[C@H]([C@@H]([C@H]1N)O)O[C@@H]([C@@H]([C@H]3O)N)O[C@@H]([C@H]3O[C@@H]([C@@H]([C@H]4O)N)O[C@@H]([C@H]4O[C@@H]([C@@H]([C@H]5O)N)O[C@@H]([C@H]5O)CO)CO)CO.Cl.Cl.Cl.Cl.Cl.Cl |
| 分子式 | C36H74Cl6N6O25 |
| 分子量 | 1203.72 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation[1][2]. [1]. Qini Zhao, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020 Apr 11;2020:2394704. [2]. Santosh K Panda, et al. Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia. PLoS Pathog. 2012;8(5):e1002717. |
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