N-p-trans-Coumaroyltyramine

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

36417-86-4

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

N-p-trans-Coumaroyltyramine 是一种从蓼属植物中分离出的 cinnamoylphenethyl amide，能作为乙酰胆碱酯酶 (AChE) 抑制剂，其 IC50 值为 122 μM。N-p-trans-Coumaroyltyramine 具有抗锥虫活性，对 T. brucei rhodesiense 作用的 IC50 值为 13.3 ?M。

Cas No.	36417-86-4
别名	N-反式-对香豆酰酪胺
Canonical SMILES	O=C(NCCC1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2
分子式	C₁₇H₁₇NO₃
分子量	283.32
溶解度	Soluble in DMSO
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	N-p-trans-Coumaroyltyramine is a cinnamoylphenethyl amide isolated from polygonum hyrcanicum, acts as an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activity with an IC50 of 13.3 µM for T. brucei rhodesiense[1][2]. IC50: 122 μM (AChE)[2] [1]. Moradi-Afrapoli F, et al. Cinnamoylphenethyl amides from Polygonum hyrcanicum possess anti-trypanosomal activity. Nat Prod Commun. 2012 Jun;7(6):753-5. [2]. Kim DK, et al. Inhibitory effect of trans-N-p-coumaroyl tryamine from the twigs of Celtis chinensis on the acetylcholinesterase. Arch Pharm Res. 2003 Sep;26(9):735-8.