CAS NO: | 68767-14-6 |
包装 | 价格(元) |
Free Sample (0.1-0.5mg) | 电议 |
10mM (in 1mL DMSO) | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
1g | 电议 |
Cas No. | 68767-14-6 |
别名 | 洛索洛芬 |
Canonical SMILES | O=C1C(CCC1)CC2=CC=C(C(C)C(O)=O)C=C2 |
分子式 | C15H18O3 |
分子量 | 246.3 |
溶解度 | DMSO: ≥ 100 mg/mL (406.01 mM) |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood) [1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3. |