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Loxoprofen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Loxoprofen图片
CAS NO:68767-14-6
包装与价格:
包装价格(元)
Free Sample (0.1-0.5mg)电议
10mM (in 1mL DMSO)电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议
1g电议

产品介绍
Loxoprofen是非甾体抗炎化合物。
Cas No.68767-14-6
别名洛索洛芬
Canonical SMILESO=C1C(CCC1)CC2=CC=C(C(C)C(O)=O)C=C2
分子式C15H18O3
分子量246.3
溶解度DMSO: ≥ 100 mg/mL (406.01 mM)
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood)

[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.