CAS NO: | 26130-02-9 |
包装 | 价格(元) |
Free Sample (0.1-0.5mg) | 电议 |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 26130-02-9 |
别名 | 夫仑替唑 |
Canonical SMILES | O=C(NC1=CC=CC=C1)NC2=NC3=CC=C(OC)C=C3S2 |
分子式 | C15H13N3O2S |
分子量 | 299.35 |
溶解度 | DMSO: ≥ 3 mg/mL (10.02 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Frentizole, an FDA-approved immunosuppressive drug, is a novel inhibitor of the Aβ-ABAD interaction.IC50 value:Target: Aβ-ABAD interaction [1]. I I Scheetz ME, D G Carlson, and M R Schinitsky Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus. Infec [2]. Hatfield SM, Hartley LW, Schmidtke JR. The immunomodulatory action of frentizole, a novel immunosuppressive agent. Immunopharmacology. 1982 Dec;5(2):169-79. [3]. Xie, Yuli; Deng, Shixian; Chen, Zhenzhang et al. Identification of small-molecule inhibitors of the Aβ-ABAD interaction. Bioorganic & Medicinal Chemistry Letters (2006), 16(17), 4657-4660. |