Zinc protoporphyrin IX

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CAS NO:

15442-64-5

包装与价格：

包装	价格(元)
10mg	电议
50mg	电议

产品介绍

化学性质

Physical Appearance	A solid
Storage	Store at RT
M.Wt	626.03
Cas No.	15442-64-5
Formula	C₃₄H₃₂N₄O₄Zn
Solubility	insoluble in H2O; insoluble in EtOH; ≥20 mg/mL in DMSO
Chemical Name	zinc;3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid
Canonical SMILES	OC(CCC1=C(C)/C([N-]/C1=C\2)=C/C(C(C)=C/3C=C)=NC3=C/C4=N/C(C(C=C)=C4C)=C\C5=C(C)C(CCC(O)=O)=C2[N-]5)=O.[Zn+2]
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Zinc protoporphyrin IX(ZnPP) is a competitive heme oxygenase-1 (HO-1) inhibitor, markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2[1].

ZnPP treatment weakened the ROS scavenging activity by PG in H2O2-treated cells.Furthermore, the beneficial effect of PG on H2O2-induced DNA damage is significantly reduced by ZnPP[1].

Reference:

[1]. Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs, 2019, 13: 17(4).