SIS3 is a potent and selective inhibitor of Smad3 function. Scientist evaluated the ability of SIS3 in the suppression of the TGF-beta1-induced type I procollagen up-regulation in human dermal fibroblasts. SIS3 also inhibited the myofibroblast differentiation of fibroblasts by TGF-beta1.
纯度:≥98%
CAS:1009104-85-1