CAS NO: | 917837-54-8 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 917837-54-8 |
别名 | AVL-3288; UCI-4083 |
化学名 | (Z)-N-(4-chlorophenyl)-3-((4-chlorophenyl)amino)-2-(3-methylisoxazol-5-yl)acrylamide |
Canonical SMILES | ClC1=CC=C(C=C1)NC(/C(C2=CC(C)=NO2)=C\NC(C=C3)=CC=C3Cl)=O |
分子式 | C19H15Cl2N3O2 |
分子量 | 388.25 |
溶解度 | <38.83mg/ml in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction[1]. CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs[1]. References: |