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Atibuclimab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2417175-94-9
包装:5mg
市场价:6390元

产品介绍
Atibuclimab 是一种针对 CD14 的嵌合单克隆抗体,由小鼠可变区和人类 IgG4 Fc 区组成。Atibuclimab 可用于肌萎缩侧索硬化症的研究。Atibuclimab 可减轻 LPS 诱导的症状,并强烈抑制 LPS 诱导的促炎细胞因子释放,同时仅延迟抗炎细胞因子可溶性 TNF 受体 I 型和 IL-1 受体拮抗剂的释放。
Cas No.2417175-94-9
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Atibuclimab, is a chimeric monoclonal antibody directed againstCD14and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis[1]. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist[2].