| CAS NO: | 107-95-9 |
| 包装 | 价格(元) |
| 500g | 电议 |
| 100g | 电议 |
| Cas No. | 107-95-9 |
| 别名 | β-丙氨酸; 2-Carboxyethylamine; 3-Aminopropanoic acid |
| 化学名 | 3-aminopropanoic acid |
| Canonical SMILES | C(CN)C(=O)O |
| 分子式 | C3H7NO2 |
| 分子量 | 89.1 |
| 溶解度 | Soluble to 100 mM in sterile water |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. Cells treated with β-alanine display significantly suppressed basal and peak ECAR (aerobic glycolysis), with simultaneous increase in glucose transporter 1 (GLUT1). Additionally, cells treated with β-alanine exhibit significantly reduced basal and peak OCR (oxidative metabolism), which is accompanied by reduction in mitochondrial content with subsequent suppression of genes which promote mitochondrial biosynthesis. Suppression of glycolytic and oxidative metabolism by β-alanine results in the reduction of total metabolic rate, although cell viability is not affected.β-alanine is shown to reduce both cell migration and proliferation without acting in a cytotoxic fashion. Moreover, β-alanine significantly increases malignant cell sensitivity to doxorubicin, suggesting a potential role as a co-therapeutic agent[1]. References: |
m.cnreagent.com