化学性质
| Physical Appearance | A crystalline solid |
| Storage | Desiccate at -20°C |
| M.Wt | 439.46 |
| Cas No. | 111358-88-4 |
| Formula | C25H21N3O4 |
| Solubility | Soluble in DMSO |
| Chemical Name | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacen-13(6H)-one |
| Canonical SMILES | O=C(NC1)C2=C1C(C(C=CC=C3)=C3N45)=C4C(N6[C@@H]7O[C@@]5(C)[C@](CO)(O)C7)=C2C8=C6C=CC=C8 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
Potent JAK2, FLT3 and TrkA inhibitor (IC50values are 0.9, 3 and < 25 nM respectively) that prevents STAT5 phosphorylation (IC50= 20 - 30 nM). Exhibits antiproliferative activityin vitro(IC50= 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disordersin vivo.
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