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Psoromic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Psoromic Acid图片
CAS NO:7299-11-8
包装与价格:
包装价格(元)
500μg电议
2.5mg电议

产品介绍
Cas No.7299-11-8
别名茶痂衣酸
化学名4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-6-carboxylic acid
Canonical SMILESCC1=C(OC)C=C(C(O)=O)C(OC2=C3C(C)=CC(O)=C2C=O)=C1OC3=O
分子式C18H14O8
分子量358.3
溶解度DMSO: Soluble,Ethanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 uM) and P. falciparum fatty acid synthesis (FAS) II. It shows cytotoxic effects on primary rat cerebral cortex and human cancer U87MG cell lines in vitro (IC50s = 79.40 and 56.22 mg/L, respectively). It also is cytotoxic against human KB cancer cells (IC50 = 31.6 uM). It shows moderate activity against liver stage P. beghei (IC50 = 31.6 uM) and drug-resistant blood stage P. falciparum (IC50 = 29.2 uM). The maximum tolerated dose in zebrafish larvae is 15.5 uM.