Guvacine HCl, the hydrochloride salt of Guvacine, is an alkaloid isolated from the nut of Areca catechu which acts as an inhibitor of GABA transporter, and dispalys modest selectivity for cloned GABA transporters with IC50s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3).
理化性质和储存条件
| Molecular Weight: 163.60
Formula: C6H10ClNO2
CAS No.: 6027-91-4
SMILES: O=C(C1=CCCNC1)O.[H]Cl |
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| Storage | -20℃ for 3 years in powder form |
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| -80℃ for 2 years in solvent |
| Technical Information | N/A |
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