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Follistatin,human recombinant protein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Follistatin,human recombinant protein图片
包装与价格:
包装价格(元)
10ug电议
20ug电议
50ug电议
1mg电议

产品介绍

描述

Gene ID:10468Accession #:P19883
Alternate Names:Human Follistatin, Follistatin, h-Follistatin, rh-Follistatin, recombinant human Follistatin, recombinant Follistatin, Follistatin.
Source:Escherichia Coli.M.Wt:31.5 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 75 mM NaCl.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Follistatin is a high-affinity activin-binding protein produced in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Follistatin acts as an activin antagonist whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). Follistatin also inhibits the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1.

The Human Follistatin cDNA encodes a 344 aa precursor protein with a 29 aa signal peptide. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids including 36 cysteine residues.

生物活性

Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells.
ED50:0.1-0.4 μg/ml in the presence of 7.5 ng/ml Activin A.