CAS NO: | 69002-84-2 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 69002-84-2 |
别名 | 5-羟基双氯芬酸 |
Canonical SMILES | ClC1=C(NC2=C(CC(O)=O)C=C(O)C=C2)C(Cl)=CC=C1 |
分子式 | C14H11Cl2NO3 |
分子量 | 312.2 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. Diclofenac is a non-selective COX inhibitor. It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 µM, respectively. Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively. |