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3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid图片
CAS NO:153666-19-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Cas No.153666-19-4
别名Deaminoneuraminic acid
化学名3-deoxy-D-glycero-D-galacto-2-nonulopyranosonic acid
Canonical SMILESO[C@H]1CC(C(O)=O)(O)O[C@]([C@H](O)[C@H](O)CO)([H])[C@@H]1O
分子式C9H16O9
分子量268.2
溶解度30mg/mL in DMSO, 10mg/mL in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is a deaminated sialic acid that was first identified at the nonreducing ends of oligosialyl chains in rainbow trout egg glycoprotein.[1] It is thought to be a precursor for the biosynthesis of other members of the sialic acid family.[2] 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid can be used to analyze nonulosonic acid residues in polysialoglycoproteins.[1]

Reference:
[1]. Nadano, D., Iwasaki, M., Endo, S., et al. A naturally occurring deaminated neuraminic acid, 3-deoxy-D-glycero-D-galacto-nonulosonic acid (KDN). Its unique occurrence at the nonreducing ends of oligosialyl chains in polysialoglycoprotein of rainbow trout eggs. The Journal of Biological Chemisty 261(25), 11550-11557 (1986).
[2]. Münster-Kühnel, A.K., Tiralongo, J., Krapp, S., et al. Structure and function of vertebrate CMP-sialic acid synthetases. Glycobiology 14(10), 43R-51R (2004).