2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
| Cas No. | 109904-27-0 |
| 别名 | 甲基(2-氯苯基)(2-氧代-2,6,7,7ALPHA-四氢噻吩并[3,2-C]吡啶-5(4H)-基)乙酸酯 |
| Canonical SMILES | ClC1=CC=CC=C1C(C(OC)=O)N2CCC(S3)C(C2)=CC3=O |
| 分子式 | C16H16ClNO3S |
| 分子量 | 337.8 |
| 溶解度 | DMF: 25 mg/mL,DMF:PBS (pH 7.2) (1:20): 0.04 mg/mL,DMSO: 20 mg/mL,Ethanol: 5 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation. |
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