化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 193.16 |
Cas No. | 1485-00-3 |
Formula | C9H7NO4 |
Solubility | insoluble in H2O; ≥2.98 mg/mL in EtOH with gentle warming and ultrasonic; ≥8 mg/mL in DMSO |
Chemical Name | 5-[(E)-2-nitroethenyl]-1,3-benzodioxole |
Canonical SMILES | C1OC2=C(O1)C=C(C=C2)C=C[N+](=O)[O-] |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic ac生物活性
Description | MNS is an inhibitor of tyrosine kinases with IC50 values of 2.5 μM, 29.3 μM and 1.7 μM for Syk, Src and p97, respectively. |
Targets | p97 | Syk | Src | | | |
IC50 | 1.7 μM | 2.5 μM | 29.3 μM | | | |