化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 246.19 |
Cas No. | 50-91-9 |
Formula | C9H11FN2O5 |
Solubility | ≥12.31 mg/mL in DMSO; ≥19.53 mg/mL in EtOH; ≥85.5 mg/mL in H2O |
Chemical Name | 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
Canonical SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Antineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways. Induces phosphorylation of Chk1 an