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UCLA GP130 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
UCLA GP130 2图片
CAS NO:339303-87-6
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
UCLA GP130 2 是一种有效的、脑渗透性和口服活性的 GP130 受体激动剂。
Cas No.339303-87-6
Canonical SMILESFC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2
分子式C15H11FN2S
分子量270.32
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.

Alam et al (2018) A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS Chem.Neurosci. 9 462 PMID:29161500