| CAS NO: | 127254-12-0 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 409.81 |
| Cas No. | 127254-12-0 |
| Formula | C19H18ClF2N3O3 |
| Solubility | insoluble in H2O; insoluble in DMSO; insoluble in EtOH |
| Chemical Name | 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid |
| Canonical SMILES | C1CC12CN(CC2N)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)C5CC5F)F |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Sitafloxacin是抗革兰氏阳性\革兰氏阴性和厌氧菌的抗生素[1].
Sitafloxacin是新型氟喹诺酮抗生素,具有光谱抗菌谱.其具有抗肠杆菌种(革兰氏阳性菌)的活性,MIC50值的范围为0.008至1 mg/ml,MIC90值的范围为0.015-2 mg/ml.对于革兰氏阴性菌,sitafloxacinis比ciprofloxacin更有效(强8倍)地抑制不动杆菌属,MIC值为0.008-8 mg/ml.此外,Sitafloxacin能够抑制厌氧菌,包括拟杆菌属\产气荚膜梭菌和消化链球菌属,MIC50值的范围为0.03至0.12 mg/ml,MIC90值为0.06至0.25 mg/ml [1].
参考文献：
[1] Milatovic D1, Schmitz FJ, Brisse S, Verhoef J, Fluit AC. In vitro activities of sitafloxacin (DU-6859a) and six other fluoroquinolones against 8,796 clinical bacterial isolates.Antimicrob Agents Chemother. 2000 Apr;44(4):1102-7.
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