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Noscapine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Noscapine HCl图片
CAS NO:912-60-7
包装与价格:
包装价格(元)
1g电议
5g电议
10g电议

产品介绍

化学性质

Physical AppearanceA solid
StorageStore at -20°C
M.Wt449.88
Cas No.912-60-7
FormulaC22H23NO7·HCl
Solubilityinsoluble in H2O; ≥10.38 mg/mL in EtOH with gentle warming; ≥18.47 mg/mL in DMSO
Chemical Name(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one;hydrochloride
Canonical SMILESCN1CCC2=CC3=C(C(=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3.Cl
运输条件蓝冰运输或根据您的需求运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。

资料参考

Noscapine hydrochloride is the hydrochloride form of Noscapine. Noscapine is an opioid alkaloid with several actions. Antagonist at Bradykinin B Receptor (bradykinin receptors) (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Additionally Noscapine binds to tubulin, arrests cells in mitosis and induces apoptosis. Blocks proliferation of human leukemia and multiple myeloma cells. Furthermore, Noscapine modulates IKK activation, suppressing the NF-κB signaling pathway. Exhibits anti-inflammatory activity. Noscapine hydrochloride is an inhibitor of Tubulin.