化学性质
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 309.32 |
| Cas No. | 178606-66-1 |
| Formula | C13H12FN3O3S |
| Solubility | insoluble in H2O; ≥11.5 mg/mL in DMSO; ≥9.14 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)urea |
| Canonical SMILES | C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)S(=O)(=O)N)F |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
资料参考
U-104是碳酸酐酶IX（CAIX）的新型脲基磺酰胺抑制剂。肿瘤体积测量显示，相对于载体对照组，U-104化合物可以抑制小鼠原发肿瘤生长。在4T1实验性癌转移模型中，它还具有抑制癌转移形成的能力。
参考文献：
Yuanmei Lou, Paul C. McDonald, Arusha Oloumi, Stephen Chia, Christina Ostlund, Ardalan Ahmadi, Alastair Kyle, Ulrich auf dem Keller, Samuel Leung, David Huntsman, Blaise Clarke, Brent W. Sutherland, Dawn Waterhouse, Marcel Bally, Calvin Roskelley, Christopher M. Overall, Andrew Minchinton, Fabio Pacchiano, Fabrizio Carta, Andrea Scozzafava, Nadia Touisni, Jean-Yves Winum, Claudiu T. Supuran, Shoukat Dedhar. Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors. Cancer Research May 1, 2011 71; 3364
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