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GP(33-41)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GP(33-41)图片
CAS NO:161928-86-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
GP(33-41) 是一种由 9 个氨基酸残基组成的多肽,它是淋巴细胞性脉络丛脑膜炎病毒 GP1 抗原决定基中的最佳序列,能够上调 RMA-S (Db Kb) 细胞表面 H-2Db分子,SC50值为 344 nM。
生物活性

GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2Dbmolecules at the RMA-S (Db Kb) cell surface with a SC50of 344 nM[1].

体外研究
(In Vitro)

GP(33-41) sensitizes MC57 and T2-Dbcells to lysis with ED50s of 0.9±0.6 and 2.5±0.7 nM[1].
The interaction between T cell receptors (TCR) and peptide-major histocompatibility complex (pMHC) antigens can lead to varying degrees of agonism (T cell activation), or antagonism. The P14 TCR recognises the lymphocytic choriomeningitis virus (LCMV)-derived peptide, GP(33-41) (KAVYNFATC), presents in the context of H-2D[2].

分子量

1016.17

Formula

C46H69N11O13S

CAS 号

161928-86-5

Sequence

Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys

Sequence Shortening

KAVYNFATC

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.