L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selectiveanti-Epstein-Barr virus (EBV)agent with anEC₅₀value of 0.03μM. L-I-OddU has low cytotoxicity with aCC₅₀value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicativeEBVDNA and viral protein synthesis^[1][2].

L-I-OddU (1 μM; H1 cells) inhibits Epstein-Barr virus (EBV) replication and decreases the linear form of EBV DNA^[1].
L-I-OddU (0.25-2 μM; 24 h; H1 and L5 cells) has a major metabolite is L-I-OddUMP and increases the amount of the mono- and diphosphate metabolites formed in H1 cells in a dose-dependent manner^[1].

340.07

C₈H₉IN₂O₅

207920-87-4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.