| CAS NO: | 1132749-48-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 生物活性 | Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor ofHDAC1,HDAC2andHDAC3(Class I),HDAC7(Class II)andHDAC11(Class IV), withID50values of 10 nM and 20 nM forHDAC1andHDAC3, respectively. Vorinostat induces cellapoptosis[1][4]. Vorinostat is also an effective inhibitor ofhuman papillomaviruse (HPV)-18DNA amplification[7]. | |||||||||
| 体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | |||||||||
| 分子量 | 269.35 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C14H15D5N2O3 | |||||||||
| CAS 号 | 1132749-48-4 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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