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As-358
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
As-358图片
CAS NO:2222042-47-7
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
As-358 对埃博拉病毒 (Ebola virus) 和马尔堡病毒 (Marburg virus) 具有抑制活性,IC50分别为 47.5 μM 和 3.7 μM。
生物活性

As-358 has inhibitory effects againstEbola virusandMarburg virus, withIC50s of 47.5 μM and 3.7 μM[1].

IC50& Target

IC50: 47.5 μM (EBOV), 3.7 μM (MARV)[1]

体外研究
(In Vitro)

As-358 (compound 3b) (0-500 μM; 10 days) exhibits inhibitory activities against EBOV and MARV[1].
As-358 (0-100 μM; 48 hours) can inhibit WT-EboV-GP and mutant D522A-EboV-GP, with IC50s of 1.7 and 2.2 μM, respectively[1].

Cell Proliferation Assay

Cell Line:Vero (infected with EBOV and MARV)[1]
Concentration:0-500 μM
Incubation Time:10 days
Result:Exhibited inhibitory activities against EBOV and MARV, with IC50s of 47.5 ± 8.2 μM and 3.7 ± 1.7 μM, SI values of 9 and 118, respectively.
分子量

293.44

Formula

C18H31NO2

CAS 号

2222042-47-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.