RIPK1-IN-12 是一种有效的RIPK1抑制剂,RIPK1-IN-12 能抑制人和小鼠细胞的坏死性凋亡,EC50值分别为 1.6 和 2.9 nM.
生物活性 | RIPK1-IN-12 is a potentRIPK1inhibitor. RIPK1-IN-12 inhibitsnecroptosisin both human and mouse cells, withEC50values of 1.6 and 2.9 nM, respectively[1]. |
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体外研究 (In Vitro) | RIPK1-IN-12 (Compound 58; 24 hours) demonstrates potent anti-necroptotic activity (EC50=1.6 nM in HT-29 cells and EC50= 2.9 nM in L929 cells)[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |