CAS NO: | 638156-11-3 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | CID 2011756 is an ATP competitivePKDinhibitor, with anIC50of 3.2 μM forPKD1in cell free assay, and also shows cellular pan-PKD inhibitory activity againstPKD2andPKD3(IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50of 3.2 μM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916in LNCaP cancer cells with an EC50of 10±0.7 μM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 μM and 0.7±0.2 μM for PKD2 and PKD3, respectively[1]. | ||||||||||||||||
分子量 | 396.87 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C22H21ClN2O3 | ||||||||||||||||
CAS 号 | 638156-11-3 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 20 mg/mL(50.39 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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