CAS NO: | 2055078-49-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | MNK8 is a potentSTAT3(signal transducer and activator of transcription 3) inhibitor. MNK8 inhibitsSTAT3activation and reduced its DNA binding ability. MNK8 shows good growth inhibition against hepatocellular carcinoma (HCC) cells. MNK8 inducesapoptosisin HCC cells. MNK8 reduces prosurvival proteins expression and migration/invasion of HCC cells[1]. | ||
IC50& Target |
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体外研究 (In Vitro) | MNK8 (50 μM, 0-48 h) increases Sub-G1 cells in a time-dependent fashion, and decreases the expression of antiapoptotic proteins such as Bcl-2, survivin, and cyclin D1[1]. | ||
分子量 | 252.27 | ||
Formula | C15H12N2O2 | ||
CAS 号 | 2055078-49-2 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |