Idetrexed 是一种胸腺嘧啶合成酶抑制剂,特异性转运到 α 叶酸受体 (α - fr) 过表达肿瘤。Idetrexed 在 1.2 nmol/L 时抑制胸腺苷酸合成酶 a。
生物活性 | Idetrexed is athymidylate synthaseinhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibitedthymidylate synthasewith aKiof 1.2 nmol/L[1][2]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |