您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Adalimumab
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Adalimumab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:331731-18-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
25mg电议
50mg电议

产品名称
阿达木单抗
Anti-Human TNF-alpha, Human Antibody
产品介绍
Adalimumab 是一种人源的单克隆 IgG1 抗体,靶向肿瘤坏死因子α (TNF-α)。
生物活性

Adalimumab is a human monoclonalIgG1antibody targeting tumour necrosis factor α (TNF-α).

IC50& Target

TNF-α[1]

体外研究
(In Vitro)

Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study[2].

体内研究
(In Vivo)

The elimination half-life (t1/2) of Adalimumab is long (~20 days)[1]. The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr-/-mice[2].

Clinical Trial
分子量

145425.42

性状

Liquid

CAS 号

331731-18-1

中文名称

阿达木单抗;阿达莫单抗

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.