CAS NO: | 2231664-45-0 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | BMT-090605 hydrochloride is a potent, selectivethe adapter protein-2 associated kinase 1 (AAK1)inhibitor with anIC50value of 0.6 nM. BMT-090605 hydrochloride shows antinociceptive activity. BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) andCyclin G-associated kinase (GAK)withIC50values of 45 nM and 60 nM, respectively. BMT-090605 hydrochloride can be used for the research of neuropathic pain[1]. | ||||||||||||
IC50& Target | IC50: 0.6 nM (AAK1); 45 nM (BIKE); 60 nM (GAK)[1] | ||||||||||||
体外研究 (In Vitro) | BMT-090605 hydrochloride shows AAK1inhibitory activity with an IC50of 0.63 nM[1]. | ||||||||||||
体内研究 (In Vivo) | BMT-090605 hydrochloride(intrathecal; 0.3-3 μg/rat) causes antinociception by inhibiting AAK1 in the spinal cord[1].
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分子量 | 400.90 | ||||||||||||
性状 | Solid | ||||||||||||
Formula | C21H25ClN4O2 | ||||||||||||
CAS 号 | 2231664-45-0 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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