Antitumor agent-85 是一种 G-quadruplex (G4) 配体，具有稳定不同 G4-DNA 结构的能力。Antitumor agent-85 具有高效的抗肿瘤特性。
| 生物活性 | Antitumor agent-85 is aG-quadruplex(G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-85 has highly effective anti-tumor properties[1]. |
体外研究
(In Vitro) | Antitumor agent-85 (compound 22a) 稳定 c-MYC Pu24T，c-MYC Pu22，CKit1，CKit2，KRAS 和 G4 的 DNA 结构[1]。Antitumor agent-85 (1-10000 nM) 抑制肿瘤类器官和癌症激活的成纤维细胞 (CAF)，IC50值分别为 193 和 2816 nM[1]。
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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