包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | RGD peptide (GRGDNP) TFA is an inhibitor ofintegrin-ligand interactions. RGD peptide (GRGDNP) TFA competitively inhibitsα5β1binding with extracellular matrice (ECM). RGD peptide (GRGDNP) TFA promotesapoptosisthrough activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) TFA plays an important role in cell adhesion, migration, growth, and differentiation[1][2][3]. | ||||||||||||||||
IC50& Target[2] |
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体外研究 (In Vitro) | RGD peptide (GRGDNP) TFA (50 μM ; preincubation for 3 hours before stretch) abolishes stretch-induced IKK activation and IL-6 mRNA expression. It shows little effect on the IKK activity and IL-6 mRNA expression in unstretched HUVECs[2]. | ||||||||||||||||
分子量 | 728.63 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C25H39F3N10O12 | ||||||||||||||||
Sequence | Gly-Arg-Gly-Asp-Asn-Pro | ||||||||||||||||
Sequence Shortening | GRGDNP | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : ≥ 50 mg/mL(68.62 mM) DMSO : ≥ 50 mg/mL(68.62 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |