CAS NO: | 1609584-72-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
2mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Mps1-IN-3 is a potent and selectiveMPS1kinase inhibitor, with anIC50of 50 nM. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | Mps1-IN-3 is a potent MPS1 kinase inhibitor, with an IC50of 50 nM. Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells with an IC50of appr 5 μM. Mps1-IN-3 (2 μM) can completely abrogates checkpoint[1]. | ||||||||||||||||
体内研究 (In Vivo) | Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models, with prolonged survival and no toxicity[1]. | ||||||||||||||||
分子量 | 537.63 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C26H31N7O4S | ||||||||||||||||
CAS 号 | 1609584-72-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 31.25 mg/mL(58.13 mM;ultrasonic and warming and heat to 60℃) 配制储备液
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以下溶剂前显示的百
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