CAS NO: | 1206170-62-8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | TC-Mps1-12 is a potent and selectivemonopolar spindle 1 (Mps1)inhibitor, with anIC50of 6.4 nM[1]. | ||||||||||||||||
IC50& Target | IC50: 6.4 nM (Mps1)[1] | ||||||||||||||||
体外研究 (In Vitro) | TC-Mps1-12 inhibits the growth of pMps1 cell lines with IC50 values of 131 nM in autophosphorylation assay[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | TC-Mps1-12 (25-100 mg/kg; p.o.; daily; for 19 days) inhibits the growth of A549 cells in a dose-dependent manner in vivo. At a dose of 100 mg/kg, TC-Mps1-12 exhibits 47% tumor growth inhibition without body weight loss[1].
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分子量 | 324.38 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C17H20N6O | ||||||||||||||||
CAS 号 | 1206170-62-8 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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