JB062 is anonmusclemyosininhibitor withIC₅₀values of 1.6, 5.4, and >100 μM for Skeletal musclemyosin, Cardiac musclemyosin, and Smooth musclemyosinII, respectively. JB062 has cytotoxic to humancancercells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy^[1].

IC50: 1.6 μM (Skeletal muscle myosin), 5.4 μM (Cardiac muscle myosin), and >100 μM (Smooth muscle myosin II)^[1]

JB062 (compound 6b; 40 μM; 24 h) 抑制 COS-7 细胞的胞质分裂^[1]。
JB062 (COS-7 细胞) 对人类癌细胞具有细胞毒性，但对正常细胞没有细胞毒性，CC₁₀值为 36 μM^[1]。

323.34

C₁₉H₁₇NO₄

2417988-00-0

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.