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ZIKV-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ZIKV-IN-2图片
CAS NO:910582-16-0
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
ZIKV-IN-2 (compound 3a) 是一种有效的 ZIKV NS5 甲基转移酶 (MTase) 抑制剂,其IC50值为 38.86 μM。ZIKV-IN-2 抑制 ZIKV 的复制和感染。ZIKV-IN-2 可用于寨卡病毒 (ZIKV) 的研究。
生物活性

ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5methyl transferase (MTase)inhibitor with anIC50value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication andinfection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV)[1].

IC50& Target

IC50: 38.86 μM (MTase)[1]

体外研究
(In Vitro)

ZIKV-IN-2 (compound 3a; 0.08-50 μM) inhibits the expression of ZIKV E protein with an EC50value of 6.17 μM and inhibits ZIKV replication and infection[1].
ZIKV-IN-2 (0.08-50 μM; 96 h) has low cytotoxicity in Vero, Huh7 and A549 cells[1].

Cell Viability Assay[1]

Cell Line:Vero, Huh7 and A549 cells
Concentration:0.08, 0.4, 2, 10, and 50 μM
Incubation Time:96 hours
Result:Exhibited low cytotoxicities to Vero cells, Huh7 cells and A549 cells with CC50>200 μM to all three cell lines.
分子量

574.75

Formula

C39H42O4

CAS 号

910582-16-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.