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DN02
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DN02图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
DN02 是一种有效的选择性 BRD8 溴域探针。DN02 对 BRD8 (1) (Ki=32 nM) 具有较高的亲和力, 其亲和力是BRD8 (2) 的 30 倍 (Ki>1000 nM)。
生物活性

DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8(1) (Ki=32 nM), which is 30-fold more affinity than BRD8 (2) (Ki>1000 nM)[1].

体外研究
(In Vitro)

DN02 has (1 nM-100 μM) low nM AlphaScreen with IC50value of 48 nM, with high selectivity over BRD9 and BRD4 in biochemical AlphaScreen assays[1].
DN02 (32 nM) has minimal off-target engagement across the bromodomain family, with modest activity against CBP/P300[1].

分子量

397.44

Formula

C22H24FN3O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.