PF-00835231 (PF-835231) is a potent 3CLpro [main protease (Mpro)] inhibitor developed by Pfizer for COVID-19 treatment. It is the active component of the phosphate prodrug PF-07304814. 3CL protease is a virally encoded protein essentialfor a broad spectrum of coronaviruses with no close human analogs. PF-00835231 exhibited potent in vitro antiviral activity against SARS-CoV-2 as a single agent. PF-00835231 has additive/synergistic activity in combination with remdesivir.

纯度：≥98%

CAS：870153-29-0