Ro 0437626 是一种选择性嘌呤能 (P2X1) 受体拮抗剂 (IC50 = 3 μM),但对 P2X2、P2X3 和 P2X2/3 受体的亲和力较低 (IC50 >100 μM)。
Cas No. | 134362-79-1 |
化学名 | N-((R)-1-(((2S,3R,4R)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl)amino)-1-oxo-3-(thiazol-4-yl)propan-2-yl)-1H-benzo[d]imidazole-2-carboxamide |
Canonical SMILES | O[C@@H]([C@@H]([C@H](CC1CCCCC1)NC([C@@H](CC2=CSC=N2)NC(C3=NC4=CC=CC=C4N3)=O)=O)O)C5CC5 |
分子式 | C27H35N5O4S |
分子量 | 525.66 |
溶解度 | <52.57mg/ml in ethanol;<52.57mg/ml in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |