NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (化合物 39) 是一种有效的APJ激动剂，Ki为 0.6 nM。NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) 可以激活 Gαi1 (EC50=0.8 nM) 并募集 β-arrestin2 (EC50=31 nM)。NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) 表现出延长的心脏作用。
| 生物活性 | NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) (compound 39) is a potentAPJagonist, with aKiof 0.6 nM. NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) can activate Gαi1 (EC50=0.8 nM) and recruit β-arrestin2 (EC50=31 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal) exhibits prolonged cardiac effects[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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![NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)图片](http://www.cnreagent.com/data/daily/2022/10/24/141457_829331_umcs_1046514.gif)