NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) (compound 40) 是 Ape13 的大环类似物，一种有效的APJ激动剂 (Ki=5.7 nM)。NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) 表现出有利的 Gα12 偏向信号传导和延长的体内半衰期。
| 生物活性 | NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) (compound 40), a macrocyclic analogue of Ape13, is a potentAPJagonist (Ki=5.7 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) exhibits a favorable Gα12-biased signaling and an increased in vivo half-life[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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![NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)图片](http://www.cnreagent.com/data/daily/2022/10/24/141457_074650_umcs_1046514.gif)