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GRK5-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GRK5-IN-4图片
CAS NO:2410794-89-5
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
CCG-265328
产品介绍
GRK5-IN-4 (Compound 16d, CCG-265328) 是一种有效的选择性共价GRK5(G 蛋白偶联受体激酶 5) 抑制剂,其IC50为 1.1 μM。GRK5-IN-4 对 GRK5 的选择性是 GRK2 的90倍。GRK5-IN-4 可用于心力衰竭研究。
生物活性

GRK5-IN-4 (Compound 16d, CCG-265328) is a potent and and selective covalentGRK5(G protein-coupled receptor kinase 5) inhibitor, with anIC50of 1.1 μM. GRK5-IN-4 shows 90-fold selectivity over GRK2. GRK5-IN-4 can be used for heart failure research[1].

IC50& Target

IC50: 1.1 ± 0.4 μM (GRK5), 1.8 ± 2 μM (GRK6), >100 μM (GRK2)[1]

体外研究
(In Vitro)

GRK5-IN-4 (Compound 16d) (0-4 h) displays a marked increase in apparent potency as a function of time[1].

分子量

483.52

Formula

C26H25N7O3

CAS 号

2410794-89-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.