CCG-273463

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CCG-273463

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2750413-99-9

包装与价格：

产品介绍

CCG-273463 是一种有效的、共价的GRK5选择性抑制剂，IC₅₀值为 8.6 nM。CCG-273463 可用于心力衰竭、肥厚型心肌病和癌症的研究。

生物活性	CCG-273463 is a potent, selective and covalentGRK5inhibitor with anIC₅₀value of 8.6 nM. CCG-273463 can be used in the research of heart failure, hypertrophic cardiomyopathy, andcancer^[1].
IC₅₀& Target	IC50: 8.6 nM (GRK5), 12 μM (GRK2)^[1].
体外研究 (In Vitro)	CCG-273463 (0.02-1 μM) potently and highly inhibits GRK5 (IC₅₀: 8.6 nM), with inhibitory rate of 93% (GRK5) and 97% (GRK6) at 1 μM^[1].
分子量	521.41
Formula	C₂₆H₂₅BrN₄O₃
CAS 号	2750413-99-9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.